University of Bordeaux Graduate School of Life and Health Sciences, Bordeaux, France INSERM 1045

 
Bourses , 中国
Université de Bordeaux, 中国

Call for proposals university of Bordeaux france, China scholarship council -PhD scholarship 2016

www.u-bordeaux.fr / www.u-bordeaux.com
Contact: elisabeth.genot@inserm.fr

CALL FOR PROPOSALS UNIVERSITY OF BORDEAUX, FRANCE

CHINA SCHOLARSHIP COUNCIL - PhD SCHOLARSCHIPS 2016

Project supervisor: Elisabeth Génot Elisabeth, contact: elisabeth.genot@inserm.fr

 

Laboratory:  European Institut for Chemistry and Biology (IECB) and INSERM 1045.

Doctoral School:  SCIENCES DE LA VIE ET DE LA SANTE, Bordeaux, France 

PhD Research Offer:

Exploitation of a murine model overexpressing a cardiovascular microRNA to explore

the role of podosomes in vascular remodeling

 

Our research team develops strategies to address the molecular mechanisms of vascular remodelling through basic research with a specific focus on the role played by endothelial cells. Endothelial cells form the vascular endothelium that lines the entire circulatory system from the heart to the smallest capillaries. We have described the formation of actin-based proteolytic microdomains called podosomes at the plasma membrane of endothelial cells that are induced under specific stimulation. There is a growing interest in addressing the physiological relavance and performance of podosomes and to determine their contribution to vascular diseases. We will set up a mouse model where the consequences of podosome formation can be addressed specifically in the vascular endothelium.

 

For more information, please contact Elisabeth Genot at elisabeth.genot@inserm.fr  and visit the following websites

 

 IECB  http://www.iecb.u-bordeaux.fr/index.php/fr/equipes/50-cell-signalling-in-health-a-disease

INSERM 1045 team 4: http://labo.fans2jeux.fr/index.php/fr/equipe/2011-05-06-15-25-15

Applications must be send to Elisabeth Genot (Elisabeth.genot@inserm.fr) preferably before February 10th 2016 in order to complete the full application forms before February 22nd 2016.